Not sure who the blonde is but I am SO glad Red She-Hulk is an alt costume for She-Hulk. Makes me wanna get the game.... Maybe one month when I get my extra 'allowance' I may swing by Gamestop and see if I can snag a copy for like 40 bucks or so.
The blonde is called Temari; she's from the series Naruto, she is a Sand Genin from the village hidden in the Sand, along with her brothers Kankuro and Gaara, they all start out as villains but eventually become allies to the heroes later on and she eventually become the love interest of, WAIT...I'm not sure that's Temari at all! Looks to be a random blonde female character from the Haruhi Suzumiya manga! Don't know too much about that manga!